INGREDIENT · BETA-HYDROXY ACID

Salicylic acid for skin: uses, side effects and pregnancy

Salicylic acid is the ingredient on most acne cleansers and spot treatments. It is also one of the few that comes up in pregnancy advice as “use with caution” rather than a flat no. Here is what that rests on, and what the evidence for home products really looks like.

You may see it written as

  • Salicylic Acid
  • BHA
  • Beta Hydroxy Acid
  • Capryloyl Salicylic Acid

What salicylic acid is

Salicylic acid has been used to treat skin disorders for more than 2,000 years.1 It exfoliates the stratum corneum, the outer layer of the skin, and it is comedolytic, which means it helps clear the plugs that form blackheads and whiteheads. The review describes it as a desmolytic agent: it works by disrupting the links between cells rather than by dissolving keratin.1

Skincare calls it a beta-hydroxy acid, or BHA, to tell it apart from the alpha-hydroxy acids such as glycolic acid.

What it does for acne

The strongest summary we found is a Cochrane review of topical acne treatments, which included salicylic acid. For people’s own rating of their acne, it found that salicylic acid may make little or no difference compared with tretinoin, based on one study of 46 people and low-quality evidence. For other comparisons the quality was low or very low.2 The review searched up to May 2019.

Most of the better-known results are for peels done by a clinician, not for home products. In a study of 35 Korean patients, 30% salicylic acid peels every two weeks for 12 weeks reduced inflammatory and non-inflammatory lesion counts and acne grade, with side effects that were tolerable in most cases.3 A review of salicylic acid peels says efficacy and safety have been documented in lighter skin (Fitzpatrick types I to III) and in darker skin (types V and VI).1

Those peel results do not tell you what a low-strength cleanser or serum does at home.

Side effects, and when it is too much

Salicylic acid can be absorbed through the skin. A 2014 review in the Journal of the American Academy of Dermatology says salicylic acid toxicity, called salicylism, is rare but can occur from topical application, and that how much is absorbed depends on the vehicle and pH.4 In practice that is a reason to take care over strength and area: a small spot treatment is not the same as a high-strength product over a large part of the body.

Unlike glycolic acid, salicylic acid did not make skin more sensitive to simulated sunlight in a small study. In 14 people, 2% salicylic acid applied for 3.5 weeks produced no significant change in redness, DNA damage or sunburn cells, while 10% glycolic acid did.5 That was a short study in a small group.

The EU’s safety committee notes that salicylic acid is an eye irritant with the potential to cause serious eye damage,6 so keep it away from your eyes.

Using salicylic acid with other products

We did not find a source saying salicylic acid must be kept apart from another active. What exists is mostly small studies of finished products, or treatments compared against each other rather than combined.

Those studies do not show what happens when you layer two products you bought separately, so read each row as what has been tried, not as proof of a good match.

  • Niacinamide

    Studied together

    A 15-centre trial of 300 people with melasma tested 30% supramolecular salicylic acid combined with 10% niacinamide against placebo for 16 weeks, and reported it was effective and safe.7 Those strengths are high, so it does not tell us how lower-strength products behave together.

  • Retinol

    No good evidence

    We found no trial of layering the two. Our retinol page covers the irritation retinoids cause on their own, which is the reason to add one at a time.

  • Benzoyl peroxide and other acne treatments

    No good evidence

    The Cochrane review compared salicylic acid with other treatments rather than combining them, and could not say which works better.2 Add one at a time.

  • Other exfoliating acids (glycolic acid, lactic acid)

    No good evidence

    The sun-sensitivity study tested glycolic acid and salicylic acid on separate patches of skin, not together.5 We found no trial of using them at the same time.

Recommended: a source advises it. Studied together: a published study used both in one product. Take care: a source gives a reason for caution. Avoid together: a source says not to combine them. No good evidence: we looked and found nothing we can cite.

Salicylic acid in pregnancy and breastfeeding

Use with caution during pregnancy and lactation: low-strength topical salicylic acid can be acceptable, but high-strength products and peels should be avoided.
Snifff’s pregnancy and nursing summary for salicylic acid

The advice is graded, and the grade follows strength. A low-strength product is a different thing from a high-strength product or a peel. The reason for the line is absorption: salicylism, the rare toxicity from salicylic acid on skin, depends on how much gets through.4

A 2026 review of cosmetic dermatology in pregnancy and lactation says that during pregnancy elective cosmetic interventions are deferred, and that high-quality safety data and formal guidelines remain limited.8 Chemical peels are one of the treatments it covers.

Ask your doctor or midwife about the specific product you use.

How the EU limits salicylic acid, and what that means in India

Both regions restrict salicylic acid. The EU adds product- and age-specific rules, including a 0.5% body-lotion cap and a ban for children under 3 except in shampoo.
Snifff’s regulatory gap summary for salicylic acid

The EU’s Scientific Committee on Consumer Safety describes the current limits for uses other than preserving a product as 3.0% in rinse-off products, 2.0% in leave-on products other than body lotion and oral products, and 0.5% in body lotion and oral products. It notes that the Cosmetic Regulation does not allow salicylic acid in products for children under 3.6 In the Cosmetics Regulation, Annex III, entry 98 sets these limits for uses other than preserving a product, and says not for children under 3, not in oral products and not for uses that may expose the lungs to inhalation; Annex V, entry 3 allows salicylic acid as a preservative at up to 0.5%, not in products for children under 3 except shampoos.9

In 2025 that committee looked at children aged 3 to 10. It found that using salicylic acid at those maximums across several products at once was not safe for that age group, and that a lower concentration, for example 0.1% in dermal products, would be.6 We have not checked whether the Commission has acted on the opinion.

Snifff’s summary says both regions restrict salicylic acid. We have not set out the Indian limits on this page.

What you will see on the label

Salicylic acid is usually listed as Salicylic Acid, and sold as “BHA” or “beta hydroxy acid”. Capryloyl salicylic acid is a different ingredient, and so are salicylate salts. The EU committee’s conclusions apply only to salicylic acid itself, not to other salicylates or salicylic acid salts.6

Snifff shows salicylic acid as Low risk. For the rest of the formula, see what the score means and how to read the list.

SnifffAs Snifff shows it

Salicylic Acid

Low risk

Pregnancy and nursing

Use with caution during pregnancy and lactation: low-strength topical salicylic acid can be acceptable, but high-strength products and peels should be avoided.

Regulatory gap

Both regions restrict salicylic acid. The EU adds product- and age-specific rules, including a 0.5% body-lotion cap and a ban for children under 3 except in shampoo.

Wording as it appears in the extension, which can change between releases.

A FEW MORE ANSWERS

Common questions about salicylic acid

Is salicylic acid an AHA or a BHA?

A BHA, or beta-hydroxy acid. Glycolic acid is the representative AHA, or alpha-hydroxy acid, and the two are studied separately.5

Can I use salicylic acid every day?

We found no trial that sets the right frequency for home products. The salicylism review is a reason to avoid large areas of high-strength products,4 so follow the product’s directions and watch how your skin responds.

Does salicylic acid make skin sensitive to the sun?

In one small study of 14 people, 2% salicylic acid did not significantly change redness, DNA damage or sunburn cells after simulated sunlight, while 10% glycolic acid did.5 That is one short study.

Is salicylic acid better than benzoyl peroxide for acne?

The Cochrane review could not say. It did not measure people’s own rating of acne in the comparison of salicylic acid with benzoyl peroxide, and the evidence on side effects was very low quality.2

Is salicylic acid safe in pregnancy?

Snifff advises caution: low-strength topical products can be acceptable, while high-strength products and peels should be avoided. See the pregnancy section above, and check with your doctor or midwife.

WHERE THIS COMES FROM

Sources

  1. Salicylic acid as a peeling agent: a comprehensive reviewArif T · Clinical, Cosmetic and Investigational Dermatology · 2015
  2. Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acneLiu H, et al. · Cochrane Database of Systematic Reviews · 2020
  3. Salicylic acid peels for the treatment of acne vulgaris in Asian patientsLee HS, Kim IH · Dermatologic Surgery · 2003
  4. A review of toxicity from topical salicylic acid preparationsMadan RK, Levitt J · Journal of the American Academy of Dermatology · 2014
  5. The effects of topically applied glycolic acid and salicylic acid on ultraviolet radiation-induced erythema, DNA damage and sunburn cell formation in human skinKornhauser A, et al. · Journal of Dermatological Science · 2009
  6. SCCS opinion on salicylic acid (CAS No 69-72-7, EC No 200-712-3): children’s exposureScientific Committee on Consumer Safety, European Commission · 2025 · SCCS/1675/25, adopted 30 April 2025
  7. Supramolecular salicylic acid combined with niacinamide in chloasma: a randomized controlled trialXiong Y, et al. · Clinical and Experimental Dermatology · 2024
  8. Cosmetic dermatology in pregnancy and lactation: a risk-benefit framework for clinical practiceKovacs T, et al. · International Journal of Dermatology · 2026
  9. Regulation (EC) No 1223/2009 on cosmetic products (consolidated text, version of 1 September 2025)European Union · 2009

This page explains an ingredient. It is not medical advice, and it is not an assessment of any product. If you are pregnant, breastfeeding, or have a skin condition, ask your doctor or pharmacist.

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